Abstract
The paper presents an analysis of the literature data concerning the autoregulation of tissue blood flow in free axial flaps. Autoregulation of microcirculation is an extremely important physiological phenomenon that ensures the stability of peripheral blood circulation and adequate metabolism in organs and tissues, regardless of fluctuations in systolic blood pressure in the range of 80-160 mm Hg. The types of sludge and their origin are described. Technologies of elimination of erythrocyte aggregates (sludge) by using dextrans of different molecular weights and pentoxifylline are discussed. Controlling the duration of primary ischemia, maintaining adequate perfusion pressure in the replants of the limbs and in free flaps, as well as reducing the peripheral vascular resistance in them, will make it possible to level the disturbances in the autoregulation of microcirculation in the reperfused tissues, ensuring the stability of capillary pressure.
Highlights
Ключевые слова: Конфликт интересов: Прозрачность финансовой деятельности: Для цитирования: ауторегуляция кровотока, свободные лоскуты, типы сладжей, декстраны, пентоксифиллин
The paper presents an analysis of the literature data concerning the autoregulation of tissue blood flow in free axial flaps
Autoregulation of microcirculation is an extremely important physiological phenomenon that ensures the stability of peripheral blood circulation and adequate metabolism in organs and tissues, regardless of fluctuations
Summary
In systolic blood pressure in the range of 80–160 mm Hg. The types of sludge and their origin are described. Technologies of elimination of erythrocyte aggregates (sludge) by using dextrans of different molecular weights and pentoxifylline are discussed. Controlling the duration of primary ischemia, maintaining adequate perfusion pressure in the replants of the limbs and in free flaps, as well as reducing the peripheral vascular resistance in them, will make it possible to level the disturbances in the autoregulation of microcirculation in the reperfused tissues, ensuring the stability of capillary pressure. Baytinger V.F., Selianinov K.V. Microcirculatory bed in reperfused flaps: modern possibilities for the correction of hemodynamic disorders (part III). Насколько микроциркуляция остается стабильной в свободных (реперфузируемых) лоскутах после их включения в кровоток. Все патологические проявления в пересаживаемых реперфузируемых тканях после различной продолжительности первичной ишемии начинаются в микроциркуляторном русле. Если первичная ишемия по времени превышает толерантность тканей к аноксии, то неизбежно в сосудах микроциркуляторного русла происходит слущивание сосудистого эндотелия, которое уже через 5 мин после запуска кровотока проявляется прогрессирующим уменьшением венозного оттока и нарастанием числа венозных эритроцитарных агрегатов [1]
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