Microcirculation of the salivary glands in patients with sialadenosis and hypogonadism before and after treatment

Abstract

BACKGROUND: Sialadenoses are often diagnosed as concomitant with certain human diseases. At the initial disease stage, it is not always possible to establish the causative pathological process. Omega-3 fatty acids have great effects on humans. The most important Omega-3 fatty acids are actively involved in the metabolism, are the building materials of cells, and help in the prevention of certain diseases.
 AIM: The Omega-3 levels in 20 patients were examined. Moreover, levels of Omega-3 in 20 patients with sialadenosis were measured before and after treatment with Omega-3 to determine the functional activity of the salivary glands depending on the concentrations in the tissues.
 MATERIAL AND METHODS: Polyunsaturated Omega-3 fatty acid is the collective name of several fatty acids; although they are not synthesized in the right quantities in humans, they are necessary for maintaining health. The most important Omega-3 fatty acids are actively involved in the metabolism and help in the prevention of cardiovascular diseases, depression, and impaired tissue microcirculation, substantially affecting the human body.
 RESULTS: The Omega-3 index before treatment was significantly reduced in all patients with sialadenosis, and it significantly increased (p 0.001) after treatment in both women and men. Moreover, the secretory function of the salivary glands significantly improved, the viscosity decreased, and the pH of the mixed saliva was restored.
 CONCLUSION: The results of this study revealed normalization of the Omega-3 index level in the erythrocyte membrane after treatment with Omega-3, improvement of the secretory activity of the salivary glands, reduction of viscosity, and restoration of the pH of mixed saliva.