Abstract

Nebulizers are essential for the delivery of aerosolized medication for respiratory patients in hospital. Microbial contamination of nebulizers increases the risk of healthcare-associated infections, presenting the critical need to identify sources of contamination in order to develop effective infection prevention and control practices in hospitals. Using an innovative microbiome-based cultivation-independent microbial source identification technique, the hospital indoor environment was identified as a significant source contributing to microbial contaminants in nebulizers, providing important information to develop strategies for targeted decontamination and enhance the effectiveness of infection prevention and control practices.

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