Abstract
The current study aims to determine the rate of surgical site infection, causal microorganism, and antibiotic sensitivity pattern in operated upper limb closed fractures at the Aga Khan University Hospital, Karachi. Cases presenting between June 2015 to October 2019, were selected from a single-centre, longitudinal, prospective orthopaedic trauma registry. Infection rate, causal microorganism, and antibiotic sensitivity pattern were determined up to six months after surgery. From among a total of 376 closed fractures, 12 encountered surgical site infection with some having late onset, giving an infection rate of 3% which is 1% higher than the international benchmark. Microorganism culture was performed on 5 (42%) patients out of which 2 (40%) were positive. Frequently used prophylactic antibiotics were first generation Cephalosporin and Co-amoxiclav in 9 (75%) patients, but all other patients required other antibiotic categories. Five patients required implant removal with antibiotic coverage. K-wire insertion required prolonged antibiotic treatment. Most of the cultures were negative in spite of the presence of infection.
Highlights
O October 2019, were selected from a single-centre, longitudinal, prospective orthopaedic trauma registry
In order to meet the 2% surgical site infection (SSI) as international benchmark of closed fracture operation site,[2] exploration of current treatment practice with post-surgical infection rate is of utmost importance
After Institutional and ERC approvals, an ongoing single-centre, prospective, longitudinal orthopaedic upper limb trauma registry was initiated in June 2015 at a tertiary care hospital
Summary
O October 2019, were selected from a single-centre, longitudinal, prospective orthopaedic trauma registry. Despite all the protective measures, infection rate is increasing, requiring selection of stringent antibiotics to control the infection.[8, 9] To reduce the SSI rate, active safety measures are highly recommended by the World Health Organisation standard guidelines.[10] In order to meet the 2% SSI as international benchmark of closed fracture operation site,[2] exploration of current treatment practice with post-surgical infection rate is of utmost importance. The aim of the current study was to assess the SSI rate in patients with upper limb closed fractures, treated surgically at a tertiary care hospital, as well as to assess the antibiotic sensitivity of causal microorganism with current prophylactic antibiotic regime. After Institutional and ERC approvals, an ongoing single-centre, prospective, longitudinal orthopaedic upper limb trauma registry was initiated in June 2015 at a tertiary care hospital.
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