Microbiology and Antimicrobial Resistance in Diabetic Foot Infections

Abstract

Diabetic foot infections (DFIs) can be caused by a wide range of microorganisms, including mainly bacteria and fungi. This class of infections poses significant medical challenges, affecting a large proportion of individuals with diabetic foot ulcers (DFUs). This chapter aims to provide a comprehensive overview of the primary microorganisms responsible for diabetic foot infections, elucidating their virulence factors, pathogenesis, and susceptibility to antimicrobial agents. It also explores the impact of antimicrobial resistance (AMR) on diabetic foot infections (DFIs), highlighting the role of biofilms in chronic diabetic foot infections and the resulting treatment difficulties, all with the goal of reducing complications. By gaining insight into the diverse spectrum of microorganisms involved in diabetic foot infections, healthcare professionals can customize treatment plans for individual patients, ultimately improving patient outcomes and quality of life.