Abstract
Background: Neonatal sepsis is a clinical syndrome characterized by systemic signs of infection and accompanied by bacteremia in the first month of life. It is a major cause of morbidity and mortality in neonatal period. The study was conducted to determine microbiological profile and antibiogram of neonatal sepsis at Omdurman Maternity Hospital.
Highlights
Neonatal sepsis is considered one of the major causes of morbidity and mortality among term and preterm infants in neonatal intensive care units (NICU) [1]
Neonatal sepsis is a systemic infection occurring in infants less than 28 days of life and is classified into early onset and late onset neonatal sepsis
Early-onset neonatal sepsis (EOS) is caused by GBS, E. coli, Streptococcus viridans, Staphylococcus aureus, and Haemophilusinfluenzae [6]
Summary
Neonatal sepsis is considered one of the major causes of morbidity and mortality among term and preterm infants in neonatal intensive care units (NICU) [1]. Neonatal sepsis is a systemic infection occurring in infants less than 28 days of life and is classified into early onset and late onset neonatal sepsis. Neonatal sepsis is a clinical syndrome characterized by systemic signs of infection and accompanied by bacteremia in the first month of life. It is a major cause of morbidity and mortality in neonatal period. Staphylococcus aureus was the most common organism in both groups of neonatal sepsis being isolated from (71, 35.7%), followed by Klebsiella pneumoniae (43, 21.2%). Gram-negative organisms were sensitive to Imepenem (97.3%) and Meropenem (80.5%) and resistant to third-generation Cephalosporins (65.3%) and Amoxicillin/Clavulanic acid (91.4%). Antimicrobial surveillance, and policy updating is necessary
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