Abstract
Esters of racemic 7-(2− trans-styryl-3-hydroxy-5-oxocyclopentenyl)- n-heptanoic acid, a key intermediate in the total synthesis of natural prostaglandins and their analogues, are subjected to the stereoselective hydrolysis of a Saccharomyces species. The resulting optically resolved enantiomorphs can be used in the chemical synthesis of F- and E-type prostaglandins.
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Schedule a callMore From: Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism
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