Abstract
Infectious complications in cancer patients are an important public health problem. The purpose of the work is microbiological monitoring of purulent complications in cancer patients for the period 2003-2015. 4209 specimens from oncological patients were examined. The bacteriological method of investigation and PCR were used. It was established that gramnegative microflora occupied one of the leading places in the occurrence of purulent complications. A significant role was played by non-fermenting gram-negative pathogens - 32.8% of the total number of clinically significant strains. The main pathogens were characterized by a high degree of resistance to antimicrobial drugs - the proportion of MDR was 23.33%, XDR - 28.33%. The main mechanism of resistance in enterobacteria was the production of beta-lactamase of extended action (81.0%) including in K.pneumoniae (87.5%), E.coli (60.0%). During the follow-up period the number of methicillin -resistant strains increased significantly: MRSA - up to 52.5%, MRSE - up to 72.0%.
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