Abstract
Background and Objectives Chronic suppurative otitis media (CSOM) is one of the common diseases in otolaryngology, and it is important to know the species of pathogens and antibiotic susceptibility for its appropriate treatment. Methicillin-resistant Staphylococcus aureus (MRSA) infections have increased, and pathogenic bacteria and antibiotic resistance are changing along with the inappropriate use and overuse of antibiotics. The aim of this study is to investigate the current bacterial profile and antimicrobial susceptibility patterns of CSOM.Subjects and Method We retrospectively investigated the bacteriological results of chronic otitis media with otorrhea in 272 outpatients who visited the department of otolaryngology from January 2017 to July 2022.Results A total of 272 cases were included in the study, of which 245 (90.1%) were diagnosed with CSOM without cholesteatoma and 27 (9.9%) were diagnosed with CSOM with cholesteatoma. Out of the total, 131 (48.2%) were male patients and 141 (51.8%) were female patients with a mean age of 60.0±14.93 years. Microbial growth was observed in 220 (80.9%) samples, but 17 (6.3%) samples showed no growth. Among the samples that showed growth, 184 (67.6%) were monomicrobial and 71 (26.1%) were polymicrobial. A total of 277 isolates were identified. The most common pathogenic organism was MRSA (23.1%), followed by <i>Pseudomonas aeruginosa</i> (19.5%), methicillin-sensitive <i>Staphylococcus aureus</i> (19.1%), and coagulasenegative staphylococci (8.3%). MRSA was highly susceptible to vancomycin, linezolid, teicoplanin (100%), sulfamethoxazole/trimethoprim, rifampin (over 96%). <i>P. aeruginosa</i> showed highest susceptibility to ceftazidime (100%), then cefepime (96.3%) and imipenem & amikacin (92.6%), and was most resistant to ticarcillin/clavulanic acid (57.4%) and ciprofloxacin (64.8%).Conclusion Considering the high prevalence of MRSA and Ciprofloxacin-resistant <i>P. aeruginosa</i>, primary empirical antibiotics should be used with caution. Furthermore, periodic surveillance on the etiological agents of CSOM and its antimicrobial susceptibility is needed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Korean Journal of Otorhinolaryngology-Head and Neck Surgery
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
