Abstract
An experimental method was developed for the determination of the extent of the partitioning of phenylmercuric nitrate in coacervate systems, as measured by the effect of the antimicrobial drug on the growth of Escherichia coli. Bacterial growth is utilized to investigate changes in the coacervate partition coefficient as a function of drug concentration. The method is sensitive for microgram quantities of this antimicrobial agent and is useful in drug partitioning at levels found in physiologic systems.
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