Abstract
Microbial hydroxylation of tedonodiol, an eremophilane alcohol, was carried out with Aspergillus niger cultures, yielding the 2α - hydroxyderivative.
Highlights
Since 1986, we have performed a project enclose in a extraction of carbonyl α,β-insaturated compounds from natural sources and chemical transformations of them, in order to provide metabolites to be tested as gastrointestinal citoprotective agents[1]
Modified Czapek broth [3] was used for performed bioconversions assays, and agar Czapek was used to maintainning the strains
Aspergillus niger ATCC 11394, Aspergillus niger Buenos Aires and a regional Aspergillus niger strain isolated from leaves of Artemisia douglassiana Besser
Summary
Since 1986, we have performed a project enclose in a extraction of carbonyl α,β-insaturated compounds from natural sources and chemical transformations of them, in order to provide metabolites to be tested as gastrointestinal citoprotective agents[1]. Modified Czapek broth [3] was used for performed bioconversions assays, and agar Czapek was used to maintainning the strains. Aspergillus niger ATCC 11394, Aspergillus niger Buenos Aires and a regional Aspergillus niger strain isolated from leaves of Artemisia douglassiana Besser.
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