Microbial And Clinical Associations Of Vaginal Mycoplasma Carriage

Abstract

Probable clinical and microbial associations of genital mycoplasmas were investigated. Archive records of 290 female patients with Mycoplasma hominis and Ureaplasma urealyticum were reviewed. A strong association was present between Mycoplasma hominis and bacterial vaginosis (BV) (OR: 4.8; 95% CI: 2.65-8.69) and absence of normal vaginal flora (NVF) (OR: 3.08; 95% CI: 1.76-5.39). Ureaplasma urealyticum was associated with BV (OR: 4.419; 95% CI: 2.43-8.03, p 1) (p=0.045) and contraceptive methods used (p=0.043). Detection of the two agents together was rather associated with BV (OR: 3.32; 95% CI: 1.82-6.04) and weakly with absence of NVF (OR: 2.15; 95% CI: 1.19-3.89). In conclusion, although causative agent of BV is still unclear, Mycoplasma hominis and Ureaplasma urealyticum alone or together have a significant co-incidence with BV and absence of normal vaginal flora.