Abstract
In forensic science, the reliable identification of human body fluids could provide important information for crime investigation. Circular RNAs (circRNAs), with an abundant, stable and tissue/developmental-stage-specific expression, may be as potential markers for forensic body fluid identification. In this study, microarray expression profiles of circRNAs were explored with total RNA extraction from venous blood, semen, saliva, vaginal secretion, and menstrual blood samples. As results, semen, saliva and venous blood could be easily distinguished from each other based on the circRNAs expression profiles, but vaginal secretions and menstrual blood displayed similar signatures. This study suggested that circRNAs extraction from forensic samples was possible and the microarray screening of circRNAs could enrich the candidates for forensic body fluid identification.
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