Abstract

The functional food market has been in a state of constant expansion due to the increasing awareness of the impact of the diet on human health. In the search for new natural resources that could act as a functional ingredient for the food industry, microalgae represent a promising alternative, considering their high nutritional value and biosynthesis of numerous bioactive compounds with reported biological properties. In the present work, the phytochemical profile, antioxidant activity, and enzymatic inhibitory effect aiming at different metabolic disorders (Alzheimer’s disease, Type 2 diabetes, and obesity) were evaluated for the species Porphyridium purpureum, Chlorella vulgaris, Arthorspira platensis, and Nannochloropsis oculata. All the species presented bioactive diversity and important antioxidant activity, demonstrating the potential to be used as functional ingredients. Particularly, P. purpureum and N. oculata exhibited higher carotenoid and polyphenol content, which was reflected in their superior biological effects. Moreover, the species P. purpureum exhibited remarkable enzymatic inhibition for all the analyses.

Highlights

  • In recent decades, there has been an increasing awareness of the impact of the diet on human health

  • The species C. vulgaris presented the lowest amount of polyphenol compounds, differing significantly from the amount found in P. purpureum

  • More than half of the compounds of this species were composed of phenolic acids, whereas P. purpureum, C. vulgaris, and N. oculata were composed mostly or exclusively of flavan-3-ols

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Summary

Introduction

There has been an increasing awareness of the impact of the diet on human health. According to the World Health Organization (WHO), dietary patterns and lifestyle habits constitute the main adjustable risk factors concerning the development of certain chronic diseases, such as obesity, type 2 diabetes, hypertension, among others, especially in developed countries [3]. This new concept is important in light of the rising cost of health care, the steady increase in life expectancy, and the desire to improve life quality [4]. Functional food may be defined as a natural or processed food that contains known biologically active compounds, which is able to provide benefits for the organism that are relevant either to one’s state of well-being and health; the management and reduction of diseases; or even physiological or psychological effects beyond the traditional nutritional role [5]

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