Abstract
Gestational diabetes mellitus (GDM) is a common metabolic abnormality which affects approximately 2-5% of pregnancies. Risk factors such as previous infants with macrosomia, strong family history of type 2 diabetes or GDM, poor glycaemic control and high pre-pregnancy body mass index (BMI) have been implicated in the development of GDM. This study was conducted to determine the prevalence of Microalbumnuria in women with risk factors for GDM and to estimate the levels of Urinary Microalbumin in these women. Fifty (50) pregnant women with risk factors for GDM and 50 controls (pregnant women without risk factors for GDM) were evaluated for Microalbuminuria. Microalbuminuria was estimated using Turbidimetric method, Random Plasma Glucose was estimated using Glucose oxidase method, serum Urea was estimated using Diacetyl Monoxime method, Creatinine was estimated using Jaffe Slot method and Albumin was estimated using Bromo Cresol Green method. The prevalence of Microalbuminuria in women with risk factors for GDM was 22%. Urinary microalbumin was significantly higher in the study subjects (56.36 ± 8.44 mg/L) than in the control (17.32 ± 4.5) mg/L. The mean ± standard error of mean of random plasma glucose in the study subjects was (5.84 ± 0.16) mmol/L and that of the control was (4.33 ± 0.14) mmol/L. The mean ± standard error of mean Serum Urea, Creatinine and Albumin were (4.1 ± 0.15) mmol/L, (0.70 ± 0.03) mg/dL, and (3.06 ± 0.05) g/dL respectively while that of the control was (3.47 ± 0.13) mmol/L, (0.63 ± 0.01) mg/dL and (2.78 ± 0.09) g/dL respectively. Obesity was strongly correlated to microalbuminuria.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Asian Journal of Research in Medical and Pharmaceutical Sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.