Abstract

A kind of medicinal polymer needle array used for skin drug delivery is proposed in this paper. The structure design, ANSYS analysis, MOLDFLOW simulation and experiment are given. The structure of the micro-needle is that the needles are distributed on a thin-walled substrate. To study the strength of the micro-needle array, ANSYS software is used to check the axial and radial stress strength. The bending strength is improved by optimizing the micro-needle geometric structure. At the same time, in view of the polymer micro-needle array forming process, MOLDFLOW simulation software is used to research the effect that melt flow direction. The results show that the needle of the polymer melts in the micro-needle the cavities flowing along the axial direction is strong. Experiments were conducted to analyze the forming of micro-needle for different polymer, and a higher accuracy polymer micro-needle array is gotten.

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