Abstract

Polycythemia is associated with an increased incidence of cerebral hemorrhage and neurodevelopmental abnormalities. Material and Methods: Whole blood and plasma viscosity (capillary viscosimeter), RBC deformability (rheoscope) and aggregation (Myrenne Aggregometer), cerebral and peripheral blood flow (plethysmography and Doppler sonography) and plasma volume (Evans blue) were studied in 21 neonates with gestational ages of 35-41 weeks. Results: The neonates were divided into two groups according to the hematocrit (group I: < .65 1/1, n=13; group II:≥65 1/1, n=8) P =art. pressure (mmHg); RBC =red blood cells: * p<.05, ** p<.005 Conclusions: Cerebral RBC flow is not affected by hematocrit, plasma volume or blood volume. The effect of V on vascular resistance is partially counterbalanced by decreasing vascular hindrance (i.e. by vasodilatation).

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