Abstract
—Follicular mycosis fungoides is an unusual variant of mycosis fungoides characterized by atypical lymphocytes showing a predilection for hair follicles (folliculotropism). Epidermotropism of lymphocytes and mucin deposition may be present to varying degrees. This malignant lymphocytic infiltrate results in follicular disruption, typically occuring as plaques, comedo-like lesions, epidermal cysts and follicular keratoses with or without alopecia.We report a 33-year-old man who presented two plaques of alopecia located on his left arm and on his right thigh for 10 years and an enlarged lymph node on inguinal region. Histology of a plaque showed an exclusive folliculotropism of atypical lymphocytes sometimes forming follicular Pautrier's microabscesses, and the lack of epidermotropism and follicular mucinosis. Histopathological study of the enlarged inguinal lymph node revealed infiltration by T-cell lymphoma. A total body CT scan demonstrated multiple enlarged lymph nodes. The patient was treated with chemotherapy, which induced a complete resolution of his patches and lymph nodes.
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