Abstract

ABSTRACTThis commentary describes scientific path and accomplishments of our late colleague, Prof. Michael D. Ter-Avanesyan, who made several seminal contributions into prion research.

Highlights

  • Despite his extensive work on prions, Michael retained an interest in the normal functions of Sup35 and Sup45

  • Galina Zhouravleva and coauthors extended this finding to Sup35 [10], while Michael’s lab, together with the lab of Mick Tuite, provided genetic evidence that Sup35 cooperates with Sup45 in yeast translation termination [11]

  • The most interesting findings were related to the prion nature of Sup35, which was proposed by Reed Wickner based on the genetic data [12]

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Summary

Introduction

Despite his extensive work on prions, Michael retained an interest in the normal functions of Sup35 and Sup45. Ter-Avanesyan, who made several seminal contributions into prion research. KEYWORDS Michael Ter-Avanesyan; Sup35; prion; amyloid; translation termination

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