Abstract

AbstractA protocol for the reaction of ketone or ester enolates with aza‐o‐quinodimethanes (aza‐o‐QMs) formed in situ is reported via a 1,4‐elimination in the presence of tetramethylammonium fluoride (TMAF). The reaction partners were reacted to provide a wide variety of substituted 2‐(tosylamino)dihydrochalcones in 45–97% yield in a single reaction sequence in one pot under mild condition. Additionally, various 2‐(tosylamino)dihydrochalcones could be easily converted to form diverse heterocycles.

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