Mgta-456, an Aryl Hydrocarbon Receptor (AHR) Antagonist Based Expansion of CD34+ Hematopoietic Stem Cells (HSC), Permits Selection of Better HLA Matched Cord Blood Units (CBUs) and Promotes Faster Neutrophil Recovery and Uniform Engraftment with Potentially Less Acute Graft-Vs-Host Disease (GVHD)

Heather Stefanski,Claudio G Brunstein,David H Mckenna,Darin Sumstad,Jeffrey S Miller,Bruce R Blazar,Todd E Defor,Anthony E Boitano,Michael P Cooke,Glen D Raffel,John C Davis,John E Wagner

doi:10.1182/blood-2019-122329

Mgta-456, an Aryl Hydrocarbon Receptor (AHR) Antagonist Based Expansion of CD34+ Hematopoietic Stem Cells (HSC), Permits Selection of Better HLA Matched Cord Blood Units (CBUs) and Promotes Faster Neutrophil Recovery and Uniform Engraftment with Potentially Less Acute Graft-Vs-Host Disease (GVHD)

Heather Stefanski, Claudio G Brunstein + Show 10 more

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https://doi.org/10.1182/blood-2019-122329

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Journal: Blood	Publication Date: Nov 13, 2019
Citations: 3

Affiliation: Fate Therapeutics (United States), University of Minnesota

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Abstract

Mgta-456, an Aryl Hydrocarbon Receptor (AHR) Antagonist Based Expansion of CD34+ Hematopoietic Stem Cells (HSC), Permits Selection of Better HLA Matched Cord Blood Units (CBUs) and Promotes Faster Neutrophil Recovery and Uniform Engraftment with Potentially Less Acute Graft-Vs-Host Disease (GVHD)

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