Abstract
One of the most enigmatic features of eukaryotic ribosomal RNA is the presence of many methylated nucleotides. The numbers of RNA methyl groups range from approximately 70 per ribosome in yeast to over 100 in vertebrates. Here it is shown that the methylated nucleotides in Xenopus laevis rRNA are broadly but non-uniformly distributed. In 18S rRNA 2'-O-methylations are partly concentrated in the 5' region and base methylations near the 3' end. In 28S rRNA methyl groups are infrequent in the 5' region, moderately frequent in the central region and abundant in an 1,100-nucleotide tract near the 3' end.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
