Abstract
In the title compound, C16H16O4, the aromatic rings are almost normal to one another, making a dihedral angle of 85.81 (10)°. In the crystal, molecules are linked by C—H⋯O hydrogen bonds, forming chains propagating along the b-axis direction. There are also C—H⋯π interactions present which link the chains, forming two-dimensional networks lying parallel to (102).
Highlights
In the title compound, C16H16O4, the aromatic rings are almost normal to one another, making a dihedral angle of 85.81 (10)
Molecules are linked by C—HÁ Á ÁO hydrogen bonds, forming chains propagating along the b-axis direction
For details of the anticancer properties of the drug Cediranib {systematic name: 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline}, for which the title compound is an important intermediate in the synthesis, see: Folkman (1996)
Summary
There are C—HÁ Á Á interactions present which link the chains, forming two-dimensional networks lying parallel to (102)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
