Abstract
Background: Exposure of newly synthesized biomaterials and drugs to humans needs a strict monitoring to minimize or prevent the after effects. One of the commonly used tests in ensuring the safety of new products is cytotoxicity testing. Cytotoxicity testing enables to observe cell growth, viability and morphological effects of biomaterials in vitro. Considering the advantages of the cytotoxicity tests, researchers employ this as a pilot test before applying in animals. Through times, many cytotoxicity assays have been developed which provide more options for the researchers. Keywords: Biomaterials, cell proliferation, cell viability, cytotoxicity, drugs, in vitro test.
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