Abstract
HLA antigens play an important role in the immunological responses to transplanted organs and in tumor surveillance and antiviral immunity. In several liver diseases qualitative and quantitative changes in the HLA gene product expression can be found on hepatocytes, bile duct epithelium and sinusoidal lining cells and these changes may affect the efficacy of the immune system in recognizing an exogenous antigen. In this paper we describe methods for quantitating the changes in HLA antigen expression occurring in the liver during various phases of hepatitis B virus infection and the way in which we have attempted to identify possible mechanisms leading to chronicity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
