Abstract

IntroductionRapid reviews (RR), using abbreviated systematic review (SR) methods, are becoming more popular among decision-makers. This World Health Organization commissioned study sought to summarize RR methods, identify differences, and highlight potential biases between RR and SR.MethodsReview of RR methods (Key Question 1 [KQ1]), meta-epidemiologic studies comparing reliability/ validity of RR and SR methods (KQ2), and their potential associated biases (KQ3). We searched Medline, EMBASE, Cochrane Library, grey literature, and checked reference lists, used personal contacts, and crowdsourcing (e.g. email listservs). Selection and data extraction was conducted by one reviewer (KQ1) or two reviewers independently (KQ2-3).ResultsAcross all KQs, we identified 42,743 citations through the literature searches. KQ1: RR methods from 29 organizations were reviewed. There was no consensus on which aspects of the SR process to abbreviate. KQ2: Studies comparing the conclusions of RR and SR (n = 9) found them to be generally similar. Where major differences were identified, it was attributed to the inclusion of evidence from different sources (e.g. searching different databases or including different study designs). KQ3: Potential biases introduced into the review process were well-identified although not necessarily supported by empirical evidence, and focused mainly on selective outcome reporting and publication biases.ConclusionRR approaches are context and organization specific. Existing comparative evidence has found similar conclusions derived from RR and SR, but there is a lack of evidence comparing the potential of bias in both evidence synthesis approaches. Further research and decision aids are needed to help decision makers and reviewers balance the benefits of providing timely evidence with the potential for biased findings.

Highlights

  • Rapid reviews (RR), using abbreviated systematic review (SR) methods, are becoming more popular among decision-makers

  • KQ2: Studies comparing the conclusions of RR and SR (n = 9) found them to be generally similar

  • KQ3: Potential biases introduced into the review process were well-identified not necessarily supported by empirical evidence, and focused mainly on selective outcome reporting and publication biases

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Summary

Introduction

Rapid reviews (RR), using abbreviated systematic review (SR) methods, are becoming more popular among decision-makers. Rapid review definition: Average time to complete (months): Topic selection Official intake/ review process: Type(s) of research question(s) rapidly reviewed: Main focus of the final review report: Protocol A priori protocol: Literature search Databases regularly searched: Identifying previous systematic reviews and primary studies: Search limits: Grey literature searching: Peer-reviewing search strategies: Study selection Number of reviewers selecting studies: Data extraction Number of data extractors: Data extracted from included studies: Evidence synthesis Summary evidence presentation: Variable; usually carries two important concepts: “need to be timely/ efficient” and “use of limited systematic review methodology”. Inform/ support patients, clinicians and decision-makers in some capacity (100% of organizations)

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