Abstract
Reference logarithmic probability curves based on data in the literature with their parameters are given for survival in Hodgkin's disease after onset and after treatment or diagnosis. Methods of reporting survival data which are better adapted for construction of reference curves are given. The value of the random number sign test and its extreme simplicity as a method of comparison of results of therapy within series and with such reference data is illustrated. The data available do not show any significant improvement in survival time since antibiotics and alkylating agents have been available. Superior results as noted from the literature have been obtained by the use of two different programs of administration of ionizing radiation. These results indicate that it is not enough to specify merely the agent used in therapy. The manner of using that agent may be equally important.
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