Abstract
The treatment of prosthesis joint infection(PJI) is a great challenge in orthopedics. In general, the treatment of PJI includes conservative and surgical therapy, but the overall effect is unsatisfactory.The biotherapy of PJI is a new method to treat PJI by destructing bioflims, specifically killing pathogenic bacteria and activating passive immunity through noval antibiotics, bioengineering, tissue engineering, drug delivery system and other methods. It is expected to solve a series of problems existing in PJI treatment. This article reviewed the progress and application prospect of PJI biotherapy. Key words: Joint prosthesis; Infection; Biological therapy
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