Abstract

A screening method for parallel Am 3+ ligand libraries is presented. The method makes use of α-radiation in combination with a photographic film to detect the complexed Am 3+. After screening and development of the film spots of varying intensities are obtained. The intensities of the spots correspond with the amount of complexed Am 3+. This allows a fast discrimination between the Am 3+ complexation efficiencies of ligands from large libraries. Depending on the exposure time of the film, activities as small as 5 Bq 241Am can be detected. Using internal standards a semi-quantitative assessment can be performed.

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