METHODOLOGY FOR THE APPLICATION OF THE SUPRAMOLECULAR COMPLEX OF IVERMECTIN "ANIVERM-2.0%" AGAINST PARASITOSIS OF HERD HORSES

Abstract

Deworming untamed herd horses is a difficult task. It is more convenient to use drugs
 by free feeding, individually or in groups in a mixture with concentrated feed. In
 this regard, we have developed a new dosage form for the treatment and prevention
 of parasitosis in herd horses by free feeding in a mixture with concentrated feed
 based on the substance ivermectin, which has a high antiparasitic activity and a wide
 spectrum of action. To obtain an antiparasitic supramolecular complex based on the
 substance ivermectin, an innovative mechanochemical technology was used using two
 water-soluble polymers of low molecular weight polyvinylpyrrollydon-17 and natural
 arabinogalactan. The aim of the work is to develop a methodology for the use of the
 supramolecular complex ivermectin "Aniverm-2.0%" against parasitosis of herd horses.
 The drug "Aniverm-2.0%" is a supramolecular complex of ivermectin, a water-soluble
 solid powder of a light beige color, tasteless, with an easily perceptible coniferous odor.
 The methodology provides a brief description of the drug, its mechanism of action,
 pharmaco-toxicological properties, the procedure for use, the timing of slaughtering
 animals and personal safety measures. According to the degree of impact on the body
 of warm-blooded animals, the drug "Aniverm-2.0%" belongs to low-toxic substances.