Abstract
(TTG)asatumor-sizeresponsemetrictopredictoverallsurvival(OS) in patients with first-line metastatic colorectal cancer treated with irinotecan,fluorouracil,andleucovorinboluswithorwithoutbevacizumab.Longitudinaltumor-sizedatafromatotalof991patientswith a median number of five measurements per patient is presented. A tumor growth inhibition model 2 is fit to individual tumor growth curvesovertimefromwhichdifferenttumor-sizeresponsemetricsare
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