Abstract
In this paper has been developed a new method for determination of Ethacridine lactate (rivanol) by laser induced fluorescence (LIF). The method has been used in order to avoid the possibility of error induced in determination of aqueous solution of rivanol by spectrophotometric method due to the shift of absorption band to short wavelength with decreasing of the concentration. The new method allows the determination of rivanol at low concentrations, in the range of 1 mM.
Highlights
In this paper has been developed a new method for determination of Ethacridine lactate by laser induced fluorescence (LIF)
In this study we develop a method based on laser induced fluorescence (LIF) in order to obtain a low detection limit for Ethacridine lactate
Ethacridine lactate is well determined by HPLCUV but the obtained detection limit is at 1.1 ng/mL (~3μM), in the ppm range
Summary
In this paper has been developed a new method for determination of Ethacridine lactate (rivanol) by laser induced fluorescence (LIF). In this study we develop a method based on laser induced fluorescence (LIF) in order to obtain a low detection limit for Ethacridine lactate. The detection limit by LIF was found to be 1.13μM while for spectrophotometric method the limit is 29.6 μM. Ethacridine lactate is well determined by HPLCUV but the obtained detection limit is at 1.1 ng/mL (~3μM), in the ppm range.
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