Abstract
Abstract At present, a main focus in the field of stent technologies is on the development of biodegradable polymeric stents. Due to inferior material characteristics of polymers compared to permanent metals stents require thicker stents struts to accomplish adequate mechanical properties. Therefore, a thermo-mechanical treatment of polymeric stents was tested, which showed a positive effect on mechanical stent characteristics.
Highlights
Materials and methods current permanent metallic drug-eluting coronary stents show excellent clinical results, the drawbacks of a permanent foreign body in the heart remain
Degradable thermoplastic polymers used for stent application, e.g. poly(L-lactic acid) (PLLA), show inferior mechanical properties compared to permanent metals
All of the stents with the different designs made of PLLA/P(4HB) could be expanded without strut ruptures
Summary
Current permanent metallic drug-eluting coronary stents show excellent clinical results, the drawbacks of a permanent foreign body in the heart remain. A focus in the field of stent technologies is on the development of biodegradable stents as the step in stent evolution. Degradable thermoplastic polymers used for stent application, e.g. poly(L-lactic acid) (PLLA), show inferior mechanical properties compared to permanent metals. To reduce the specific issues of biodegradable. To determine the effect of thermo-mechanical treatment of polymeric stents on their mechanical properties three stent designs were compared. Design 1 and design 2 (Figure 1a, b) consist of interlaced rhombi and differ with regard to their strut lengths. Design 3 (Figure 1c) features double-strut rings. These designs are aimed at providing radial strength in conjunction with high axial bending stiffness
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