Method for studying the rheological properties of parotid saliva using controlled dynamic sialometry

Abstract

Relevance. Sialometry may determine the nature of x erostomia, and the results should be representativ e. The study aimed to increase the information value of the parotid gland secretory function examination by determining saliva rheological properties during the c ontrolled dynamic sialometry.Materials and methods. Twenty-two patients with xerostomia had a controlled dynamic sialometry in two stages with simultaneous saliva sampling using a Lashley capsule and a catheter. At the first stage, the capsule was on the right, the catheter was on the left; at the second stage their places were swapped. In 44 comparison pairs, the capsule parameters were the control, the catheter parameters were studied. The method of stimulated ductal sialometry according to Andreeva T.B. formed a basis of the study. The study eliminated the technological error of sialometry, the rheological state of saliva was determined by subtracting the catheter index from the capsule index. The study was approved by the ethics committee (No. 02-21 dated February 18, 21), voluntary. Difference significance was statistically assessed using the Student 's t-test. The results were significant at p ≤ 0.05.Results. The analysis of 44 comparison pairs showed a priority (t = 7.317; p < 0.001) of the number of cases with large capsule scores (n = 34; 77.3%) compared catheter (n = 7; 15.9%). Therefore, capsule sialometry is more representative. Capsule sialometry (n = 44) showed hyposalivation in 11 cases (25.0%), secretion values were normal (t = 5.416; p < 0.001) in the remaining 33 cases (75.0%). Normal rheological condition of saliva was significantly more common in the hyposalivation group – objective xerostomia (t = 1.900; p < 0.05); rheological disorders were significantly more common in the group with normal secretion - subjective xerostomia (t = 7.729; p < 0.01).Conclusion. Controlled dynamic sialometry determines the technological error and objectifies sialometry parameters; explores saliva rheological condition, which affects the performance of sialometry when using a catheter. Objective xerostomia is characterized by hyposalivation with a secondary significance of saliva rheological condition. Subjective xerostomia can occur only due to a saliva rheological disorder .