Abstract
A new method is described which for the first time makes possible simultaneous measurements of local changes of blood flow and acidity in the human gastric mucosa. It has been demonstrated that variations of blood flow and of acidity are basically independent of each other. On the other hand, there are agents and combinations of drugs by means of which these two functions of the stomach can be influenced in regular ways. Histamine induces a rise in blood flow and acidity. The adrenaline derivative Alupent, however, combined with an anticholinergic, normally induces a rise in blood flow and a decrease of acidity. This combination may offer a favorable basis for the healing of peptic ulcers.
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