Abstract

Summary Two cases of methemoglobinemia in newborn infants are presented. Theyappeared to be caused by nitrates in the well water used for the dilution of powdered milk in the formula. In the first case, the acute stage was successfully treated with transfusions. In the second case, the first attack was healed by methylene blue. However,treatment was begun too late to save the patient in a, second attack. The literature of the subject is briefly reviewed. The pathogenesis of the disease is discussed in connection with the findingof large amounts of nitrates in the well water and of small amounts of nitrites in the blood of the second patient.

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