Abstract

Methemoglobin forms in aqueous solutions of hemoglobin and in intact rats after exposure to ionizing radiation. For moderate doses, the degree of methemoglobinemia is a linear function of dose. In the sub-lethal dose range, the methemoglobinemia is comparable to the random variation in normal values. A secondary methemoglobinemia was observed in rats 3 to 8 hours postirradiation.

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