Abstract
Nitrobenzene (NBZ) is a pale-yellow coloured compound, moderately water-soluble oily liquid, and odour similar to bitter almonds. It is commonly used in the manufacture of aniline, benzidine, quinolone, drugs, dyes, solvent in shoe, metal polishes, and in screen printing]. It is a potent oxidizer of the iron moiety of haemoglobin causing methemoglobinemia leading to its inability to transport oxygen. Clinical features of nitrobenzene poisoning include gastric irritation, nausea, vomiting, cyanosis, drowsiness, seizures, coma and finally respiratory failure culminating in death. Intravenous methylene blue and ascorbic acid are commonly used for treatment of significant poisoning.
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