Abstract

Methanol is found in antifreeze solutions, windscreen-washing fluid, duplicating fluid, paint remover, varnishes and shoe polish, and is used widely as a solvent and to denature ethanol. Almost all cases of acute methanol toxicity result from ingestion. Rarely, poisoning follows inhalation or dermal absorption. Absorption following ingestion is rapid; peak methanol concentrations occur within 30-60 minutes. Ingestion of as little as 10 ml of pure methanol has caused permanent blindness and 30 ml is potentially fatal, though individual susceptibility varies widely.

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