Abstract
BackgroundHigh levels of depressive symptoms often occur among individuals that use or that are dependent on methamphetamine (MA). Thailand is currently experiencing an epidemic of MA use among youth. Understanding the nature of the relationship between depressive symptoms and MA use and identifying those most at risk can further understanding of prevention and treatment options for youth who use MA and present with depressive symptoms.MethodsIn 2011, we conducted a cross sectional epidemiologic study that examined associations between MA use and high levels of depressive symptoms among adolescents and young adults aged 14–29 living in Chiang Mai province, Thailand. A combination of cluster and systematic sampling was conducted to obtain a study sample of participants actively recruited in Chiang Mai province. Depressive symptoms were measured using a Thai translation of the Centers for Epidemiologic Studies Depression scale (CES-D). The independent variables measured reported lifetime and recent MA use within the past 3 months. Multivariate logistic regression models were used to assess associations between MA use and high levels of depressive symptoms.ResultsApproximately 19 % (n = 394) of the sample reported ever having consumed MA and 31 % (n = 124) of lifetime users reported recent MA use within the past 3 months. Recent MA use was associated with high levels of depressive symptoms (aPOR recent use: 2.60, 95 % CI: 1.20, 5.63).ConclusionsThis is one of the first studies to examine the association between MA use and high levels of depressive symptoms in a general Thai population. The odds of having high levels of depressive symptoms was significantly greater among recent MA users compared to non-users. These findings support the need for policies, programs and interventions to prevent and treat depressive symptoms presenting among MA using Thai adolescents and young adults in rural Chiang Mai province, Thailand to aid in cessation of MA use. Furthermore, additional research is needed to investigate treatment options for adolescents and young adults in Thailand that use MA and present with high levels of depressive symptoms.
Highlights
High levels of depressive symptoms often occur among individuals that use or that are dependent on methamphetamine (MA)
This research demonstrates an association between methamphetamine and depressive symptoms, controlling for confounding, among a general population of Thai adolescents and young adults in Chiang Mai Province, Thailand
Studies in various settings have found a high prevalence of MA users reporting a lifetime history of depression, with prevalence estimates ranging between 50 % of men and 68 % of women and 57 % of MA users reporting the presence of depressive symptoms in the past year compared to 32 % among non-users [9, 10]
Summary
High levels of depressive symptoms often occur among individuals that use or that are dependent on methamphetamine (MA). In a study of young Thai MA users aged 18–25 years, authors observed a prevalence of 35 % of participants presenting with high levels of depressive symptoms [12]. Most studies are limited by design or methodology because they have assessed the prevalence of depression among amphetamine or MA users using various instruments to measure depressive symptoms, and most have examined limited data among health seeking populations that may not be representative of all users. Most of these studies have not been conducted among populations in low- and middle-income countries and only one was conducted among Thai youth. No studies of general Thai populations in rural areas have been conducted to our knowledge
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