Abstract
Background Methadone is an effective analgesic and it is widely used to suppress withdrawal symptoms from other opiates. Its consumption is usually associated with concomitant drug use in heroin addicts, and this combination is a possible risk factor for lethal outcome. The aim of this study was to analyze characteristics of methadone-related deaths (MRDs), and to evaluate the concomitant use of the drugs that can contribute to methadone toxicity.
Highlights
Methadone is an effective analgesic and it is widely used to suppress withdrawal symptoms from other opiates
The aim of this study was to analyze characteristics of methadone-related deaths (MRDs), and to evaluate the concomitant use of the drugs that can contribute to methadone toxicity
Methadone was found (17.5 % of MRDs); 47.5% of MRDs was associated with other drugs – the average number of associated drugs was 3.5, while in blood samples of 35% of MRDs other illicit drugs were identified
Summary
Methadone is an effective analgesic and it is widely used to suppress withdrawal symptoms from other opiates. The aim of this study was to analyze characteristics of methadone-related deaths (MRDs), and to evaluate the concomitant use of the drugs that can contribute to methadone toxicity
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