Abstract
Metformin sik kullanilan, metabolizma uzerine pozitif etkileri olan bir oral anti-diyabetik ilactir. Karbohidrat metabolizmasina, lipid profiline ve kilo dengesine etkileri ve diger ilaclara gore daha ucuz olmasi gelismekte olan ulkelerde sikca kullanilan bir ilactir. Hemodiyaliz gerektiren kronik bobrek yetmezligi gibi kronik hastaliklar metformin kullanimi icin kontrendikasyon olsa da mevcut bulgular metforminin diger anti-diyabetik ilaclarla karsilastirildiginda laktik asidoz icin artmis riskinin bulunmadigini gostermektedir. Bu vakada acil servise bilinc bulanikligiyla gelen metformin tedavisi ve son donem bobrek yetmezligi nedeniyle hemodiyaliz uygulanan bir hastayi sunduk. Metformin iliskili laktik asidoz tanisi konmus ve hastanin klinigi hemodiyaliz sonrasi normale donmustur. (JAEM 2012; 11: 133-4) Anahtar kelimeler: Metformin, diyabet, laktik asidoz Abstract
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