Abstract
Objective To assess the effect of Metformin and Acarbose plus dietary and exercise therapy on preventing IFG population from becoming diabetes mellitus.Methods 112 subjects with IFG were equally divided into control group and trial group in accordance with the index of age,sex,SBP,DBP,and BMI.The control group was treated with placebos plus dietary and exercise therapy.And the trial group was orally given Metformin (0.25 g,t.i.d) and Acarbose (50 mg,t.i.d) plus diet and exercise therapy.12 months after treatment,the indexes of FPG,2hPG etc.was detected in all subjects and compared between the 2 groups.Results All the indexes descended in the 2 groups after treatment,,but descended more in the trial group.There were significant differences in the indexes of FPG,FINS,2hPG,2hINS,and HbA1c in the trial group before and after treatment (P＜0.05).Conclusions Metformin and Acarbose plus dietary and exercise therapy for IFG population can control the blood glucose level effectively and prevent or postpone the form of diabetes mellitus. Key words: IFG; Metformin; Acarbose; Intervention treatment
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
