Abstract
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of malignant tumour in the pancreas. It is a highly aggressive tumour with poor prognosis. The liver and peritoneum are the most common sites of metastasis, and metastasis to colon and cervix are extremely rare. We herein report a case of metastatic PDAC presented as a cervical mass and rectal mass. Biopsies were taken from the rectal mass, cervical mass, and pancreatic mass. They show similar morphology and same immunostaining results, including loss of nuclear staining for SMAD4. In viewing unusual morphology and a lack of precursor lesions in small biopsies, one should alert the possibility of metastasis. Correlation with clinical history and radiological examination and the use of appropriate immunohistochemistry are also essential for making the correct diagnosis.
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