Metastatic Medullary Thyroid Carcinoma without Evident Thyroid Nodules: A Rare Presentation

Abstract

Introduction: Uncommon thyroid and neuroendocrine tumor; medullary thyroid carcinoma (MTC) is a rare, aggressive malignancy, with a 10-year survival rate of roughly 50%. Clinical presentation of MTC differs from sporadic to familial variety, but frequently it is showcased as a painless thyroid nodule. Metastatic medullar carcinoma without nodules is scanty, adding to the unpredictable behaviors of this entity. Case Presentation: Thus; the report of this rare presentation in 57-year-old patient with cervical metastatic lymphadenopathy, and a normal sized thyroid and no distant metastases, to which the patient underwent a chemo/ radiotherapy because the encompassment of the vascular axis. Conclusion: Metastasis medullary thyroid carcinoma with normal-size thyroid is somehow unheard of in the literature, as this rare aggressive tumor is usually diagnostic at a stage where the thyroid nodule is accompanied with lymph node metastases.