Abstract
BackgroundMalignant glomus tumors are extremely rare soft tissue tumors that are rich in tumor vessels. Due to its rarity, no treatment strategy other than resection has been established. Pazopanib, a multikinase inhibitor, is expected to improve the prognosis of patients with soft tissue sarcoma. However, there are no reports on the clinical outcomes of pazopanib in patients with malignant glomus tumors. Case presentationA 74-year-old man with a history of neurofibromatosis type 1 was diagnosed with a malignant glomus tumor on his left thigh, with multiple lung metastases at initial presentation. Doxorubicin was administered followed by pazopanib; however, tumor progression was not arrested. ConclusionTo the best of our knowledge, this is the first reported case of a malignant glomus tumor treated with pazopanib. Further investigations on chemotherapy in patients with malignant glomus tumors are needed.
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