Abstract
Approximately 30–50% of patients with autosomal dominant polycystic kidney disease (ADPKD) develop renal infection [1]. Cyst infection and acute pyelonephritis are the most common infectious complications, although bacteraemia, perinephric and extrarenal abscess can also be seen. The problem is that eradication of cyst infections with conventional antibiotics is sometimes unsuccessful chiefly because of poor penetration of antibiotics into infected cysts. As a result, a significant portion of patients with ADPKD suffer from latent cyst infection, which may result in bacteraemia and/or metastatic extrarenal infection. We describe here a case of ADPKD whose intracranial subdural empyema indicated a metastatic abscess from an uncontrolled cyst infection accompanying ADPKD.
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