Abstract
Basal cell carcinoma is the most common skin cancer, characterised by a slow growing behavior, metastasis are extremely rare, and it occurs in less than 0, 1% of all cases. Giant basal cell carcinoma is a rare form of basal cell carcinoma, more aggressive and defined as a tumor measuring more than 5 cm at its largest diameter. Only 1% of all basal cell carcinoma develops to a giant basal cell carcinoma, resulting of patient's negligence. Giant basal cell carcinoma is associated with higher potential of metastasis and even death, compared to ordinary basal cell carcinoma. We report a case of giant basal cell carcinoma metastaticin lung occurring in a 79 years old male patient, with a fatal evolution after one course of systemic chemotherapy. Giant basal cell carcinoma is a very rare entity, early detection of these tumors could prevent metastasis occurrence and improve the prognosis of this malignancy.
Highlights
Basal cell carcinoma (BCC) is the most common malignant skin tumor in the world with 750,000 cases reported annually in the United States alone [1, 2]; it is more common in males than females
Their potential of metastasis is higher than ordinary basal cell carcinoma and the prognosis is very poor
We present a case of giant basal cell carcinoma occurring in a 79 years old male patient metastaticin lungs with a fatal evolution
Summary
Basal cell carcinoma (BCC) is the most common malignant skin tumor in the world with 750,000 cases reported annually in the United States alone [1, 2]; it is more common in males than females. We present a case of giant basal cell carcinoma occurring in a 79 years old male patient metastaticin lungs with a fatal evolution. A diagnosis of a giant basal cell carcinoma metastatic to the lungs was established; the patient had an ECOG performance status of 2, a blood workup showed he had normal renal function. He received only one course of 5FU-ceplatin decided to interrupt the treatment. He died one month after the beginning of treatment
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