Metastatic colorectal cancer presenting with malignant pleural effsion - a self-experience study

Abstract

INTRODUCTION : Colorectal cancer (CRC) advanced stage (stage IVA) is characterized by distant metastasis in one organ or in one site. The aim of this study is to present a relatively rare localization of CRC dissemi­nation, i.e. pleural metastases clinically presenting with malignant pleural effusion. PATIENTS AND METHODS : A total of 12 patients, 10 males and two females at a mean age of 61.4±13.3 years (range, 39-78 years) with malignant pleural effusion because of CRC were included in this four-year study (2012-2016). Physical examination and Karnofsky performance status score were evaluated. Radio­graphic studies were used to establish pleural effusion. Pleural effusion drainage and pleural fluid cytolog­ical examinations were performed. Patients` survival rate was established. RESULTS : Pleural metastasis developed approximately 1.8±0.7 years after radical operation in all the pa­tients. Patient`s Karnofsky performance status score was ≤50. Pleural effusion evacuation was accomplished by tube thoracostomy in all the patients. The cytological examination established adenocarcinoma cells in the pleural effusion. The mean patient`s survival rate was 3.1±1.9 months. CONCLUSION : This study described a rare localization of CRC metastasis in the pleural cavity character­ized by an extremely low patient`s survival rate. Scr Sci Med 2017; 49(3): 35-39