Abstract

Small cell carcinoma of the ovary, hypercalcemic type, can lead to metastatic calcinosis-the deposition of calcium in the alkaline walls of acid-secreting organs. The disease primarily affects young women and its course is rapidly progressive and invariably fatal. There is typically no elevation in parathormone levels noted, however, as increased serum calcium levels are the result of a paraendocrine phenomenon. Metastatic calcinosis can be seen when the calcium X phosphorous product exceeds 60 mg/dL. Precipitation of resultant calcium salts occurs in organs such as the stomach, kidneys, and lungs.

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